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Results 1 to 25 of 29

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The selective advantage of α1-antitrypsin deficiencyLOMAS, David A.American journal of respiratory and critical care medicine. 2006, Vol 173, Num 10, pp 1072-1077, issn 1073-449X, 6 p.Article

Molecular mousetraps, α1-antitrypsin deficiency and the serpinopathiesLOMAS, David A.Clinical medicine. 2005, Vol 5, Num 3, pp 249-257, issn 1470-2118, 9 p.Article

Promiscuous beta-strand interactions and the conformational diseasesCHOW, Michelle K. M; LOMAS, David A; BOTTOMLEY, Stephen P et al.Current medicinal chemistry. 2004, Vol 11, Num 4, pp 491-499, issn 0929-8673, 9 p.Article

Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genomeWAN, Emily S; WEILIANG QIU; BACCARELLI, Andrea et al.Human molecular genetics (Print). 2012, Vol 21, Num 13, pp 3073-3082, issn 0964-6906, 10 p.Article

Changes in Forced Expiratory Volume in 1 Second over Time in COPDVESTBO, Jørgen; EDWARDS, Lisa D; LOMAS, David A et al.The New England journal of medicine. 2011, Vol 365, Num 13, pp 1184-1192, issn 0028-4793, 9 p.Article

Variants in FAM13A are associated with chronic obstructive pulmonary diseaseCHO, Michael H; BOUTAOUI, Nadia; LANGE, Christoph et al.Nature genetics. 2010, Vol 42, Num 3, pp 200-202, issn 1061-4036, 3 p.Article

Polymers of Z α1-antitrypsin co-localize with neutrophils in emphysematous alveoli and are chemotactic in vivoMAHADEVA, Ravi; ATKINSON, Carl; ZHENJUN LI et al.The American journal of pathology. 2005, Vol 166, Num 2, pp 377-386, issn 0002-9440, 10 p.Article

Association between conformational mutations in neuroserpin and onset and severity of dementiaDAVIS, Richard L; SHRIMPTON, Antony E; PICCARDO, Pedro et al.Lancet (British edition). 2002, Vol 359, Num 9325, pp 2242-2247, issn 0140-6736Article

Prevalence and Risk Factors for Liver Involvement in Individuals with PiZZ-related Lung DiseaseDAWWAS, Muhammad F; DAVIES, Susan E; GRIFFITHS, William J. H et al.American journal of respiratory and critical care medicine. 2013, Vol 187, Num 5, pp 502-508, issn 1073-449X, 7 p.Article

Genome-Wide Association Studies Identify CHRNA5/3 and HTR4 in the Development of Airflow ObstructionWILK, Jemma B; SHRINE, Nick R. G; LOTH, Daan W et al.American journal of respiratory and critical care medicine. 2012, Vol 186, Num 7, pp 622-632, issn 1073-449X, 11 p.Article

Randomised controlled trial for emphysema with a selective agonist of the γ-type retinoic acid receptorSTOLK, Jan; STOCKLEY, Robert A; MANNES, Gregorius P. M et al.The European respiratory journal. 2012, Vol 40, Num 2, pp 306-312, issn 0903-1936, 7 p.Article

Association of TRPV4 gene polymorphisms with chronic obstructive pulmonary diseaseGUOHUA ZHU; GULSVIK, Amund; BAKKE, Per et al.Human molecular genetics (Print). 2009, Vol 18, Num 11, pp 2053-2062, issn 0964-6906, 10 p.Article

αI-Antitrypsin deficiency, chronic obstructive pulmonary disease and the serpinopathiesEKEOWA, Ugo I; GOOPTU, Bibek; CROWTHER, Damian C et al.Clinical science (1979). 2009, Vol 116, Num 11-12, pp 837-850, issn 0143-5221, 14 p.Article

Small molecules block the polymerization of Z α1-antitrypsin and increase the clearance of intracellular aggregatesMALLYA, Meera; PHILLIPS, Russell L; LOMAS, David A et al.Journal of medicinal chemistry (Print). 2007, Vol 50, Num 22, pp 5357-5363, issn 0022-2623, 7 p.Article

Characteristics, stability and outcomes of the 2011 GOLD COPD groups in the ECLIPSE cohortAGUSTI, Alvar; EDWARDS, Lisa D; CRIM, Courtney et al.The European respiratory journal. 2013, Vol 42, Num 3, pp 636-646, issn 0903-1936, 11 p.Article

Inflammatory Biomarkers Improve Clinical Prediction of Mortality in Chronic Obstructive Pulmonary DiseaseCELLI, Bartolome R; LOCANTORE, Nicholas; LOMAS, David A et al.American journal of respiratory and critical care medicine. 2012, Vol 185, Num 10, pp 1065-1072, issn 1073-449X, 8 p.Article

Genome-wide association study of smoking behaviours in patients with COPDSLEDLINSKI, Mateusz; CHO, Michael H; CRAP, James D et al.Thorax. 2011, Vol 66, Num 10, pp 894-902, issn 0040-6376, 9 p.Article

Susceptibility to Exacerbation in Chronic Obstructive Pulmonary DiseaseHURST, John R; VESTBO, Jørgen; CALVERLEY, Peter et al.The New England journal of medicine. 2010, Vol 363, Num 12, pp 1128-1138, issn 0028-4793, 11 p.Article

Airway Wall Thickening and Emphysema Show Independent Familial Aggregation in Chronic Obstructive Pulmonary DiseasePATEL, Bipen D; COXSON, Harvey O; WOUTERS, Emiel F. M et al.American journal of respiratory and critical care medicine. 2008, Vol 178, Num 5, pp 500-505, issn 1073-449X, 6 p.Article

Cystic fibrosisGEDDES, Duncan; LOMAS, David A; JOHNSON, Simon R et al.Clinical medicine. 2007, Vol 7, Num 5, pp 445-449, issn 1470-2118, 5 p.Article

Expression of the serine protease inhibitor neuroserpin in cells of the human myeloid lineageKENNEDY, Sarah A; VAN DIEPEN, Angela C; DUNBAR, P. Rod et al.Thrombosis and haemostasis. 2007, Vol 97, Num 3, pp 394-399, issn 0340-6245, 6 p.Article

A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19p13CHO, Michael H; CASTALDI, Peter J; LANGE, Christoph et al.Human molecular genetics (Print). 2012, Vol 21, Num 4, pp 947-957, issn 0964-6906, 11 p.Article

Variable DNA Methylation Is Associated with Chronic Obstructive Pulmonary Disease and Lung FunctionWEILIANG QIU; BACCARELLI, Andrea; DEMEO, Dawn L et al.American journal of respiratory and critical care medicine. 2012, Vol 185, Num 4, pp 373-381, issn 1073-449X, 9 p.Article

Genome-wide Association Study Identifies BICD1 as a Susceptibility Gene for EmphysemaXIANGYANG KONG; CHO, Michael H; SILVERMAN, Edwin K et al.American journal of respiratory and critical care medicine. 2011, Vol 183, Num 1, pp 43-49, issn 1073-449X, 7 p.Article

Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary diseaseBREHM, John M; HAGIWARA, Koichi; CHO, Michael H et al.Thorax. 2011, Vol 66, Num 12, pp 1085-1090, issn 0040-6376, 6 p.Article

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